Stannous Chloride → HCID 178507449, compound

Participants

Reaction Steps

5-(4-Fluorophenyl)-2-(4-nitrophenyl)-N-(2-thiazolyl)-imidazole-4-carboxamide obtained in Example 57 is suspended in methanol and ice-cooled. To the suspension is added a solution of tin(II) chloride 6 hydrate in 6 M hydrochloric acid solution and the mixture is reacted and treated in the same manner as in Example 48 to give 2-(4-aminophenyl)-5-(4-fluorophenyl)-N-(2-thiazolyl)-imidazole-4-carboxamide.

Provenance & Evidence