HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 178480817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 178522570 | HCID 178522570 | — |
| Product | HCID 178480817 | HCID 178480817 | 177.5% |
Reaction Steps
5-(4-Chloromethylphenyl)-2-(4-nitrophenyl)-N-(2-thiazolyl)-imidazole-4-carboxamide (900 mg) obtained in Example 94 and 1-methylpiperazine (309 mg) were reacted and treated in the same manner as in Example 95 to give 5-(4-(4-methylpiperazin-1-ylmethyl)-phenyl)-2-(4-nitrophenyl)-N-(2-thiazolyl)imidazole-4-carboxamide trihydrochloride (742 mg), melting point 248-252° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288061B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-27d12b01cc1e4255a733fe8fe2712c7a |
| Source note | uspto-grants-2001_09 |