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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1595430Generated: October 30, 2026

2-(Dimethylamino)ethanol → HCID 178483867, compound

https://huagongshe.com/reaction/1595430

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Dimethylamino)ethanolHCID 7902—
ReactantTriphenylphosphineHCID 11776—
Reactantethyl N-ethoxycarbonyliminocarbamateHCID 220568—
ReactantHCID 178522578HCID 178522578—
ProductHCID 178483867HCID 178483867—

Reaction Steps

5-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-N-(2-thiazolyl)-imidazole-4-carboxamide, 2-dimethylaminoethanol, triphenylphosphine and diethyl azodicarboxylate are reacted and treated in the same manner as in Example 24 to give 5-(4-fluorophenyl)-2-(4-(2-dimethylaminoethyloxy)phenyl)-N-(2-thiazolyl)imidazole-4-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06288061B1
Source datasetuspto-grants-2001_09
ORD IDord-65e8143631014b3c8d1ddfa6c390487a
Source noteuspto-grants-2001_09