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HRID1595430

反应详情

EQUATION

反应方程式

HRID 1595430 的结构方程式

REACTANTS

反应物

4
结构：CN(C)CCO
HCID7902

Dimethylaminoethanol

C4H11NO

结构：c1ccc(P(c2ccccc2)c2ccccc2)cc1
HCID11776

Triphenylphosphine

C18H15P

结构：CCOC(=O)N=NC(=O)OCC
HCID220568

Diethyl azodicarboxylate

C6H10N2O4

结构：O=C(Nc1nccs1)c1nc(-c2ccc(O)cc2)[nH]c1-c1ccc(F)cc1
HCID178522578

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)CCOc1ccc(-c2nc(C(=O)Nc3nccs3)c(-c3ccc(F)cc3)[nH]2)cc1
HCID178483867

未命名化合物

PROCEDURE

实验过程

5-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-N-(2-thiazolyl)-imidazole-4-carboxamide, 2-dimethylaminoethanol, triphenylphosphine and diethyl azodicarboxylate are reacted and treated in the same manner as in Example 24 to give 5-(4-fluorophenyl)-2-(4-(2-dimethylaminoethyloxy)phenyl)-N-(2-thiazolyl)imidazole-4-carboxamide.

WORKUP

后处理

  1. additiontreated in the same manner as in Example 24