HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → HCID 178486708, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | 4-Chloro-7-(2-chloroethoxy)-6-methoxy-3-quinolinecarbonitrile | HCID 11109252 | — |
| Reactant | HCID 178507366 | HCID 178507366 | — |
| Solvent | 2-Methoxyethanol | HCID 8019 | — |
| Product | HCID 178486708 | HCID 178486708 | 82% |
Reaction Steps
The title compound was prepared by the procedure of Example 166 using 0.442 g of 7-(2-chloro-ethoxy)-4-chloro-6-methoxy-quinoline-3-carbonitrile, 0.22 g 5-amino benzotriazole, 0.190 g of pyridine hydrochloride and 15 ml of 2-methoxyethanol to give 0.48 g (82%) of the desired product :mass spectrum (electrospray m/e): M+H=394.8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288082B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-3866c0f60cc44e098a124798d7d92718 |
| Source note | uspto-grants-2001_09 |