HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazol-6-amine → HCID 10223129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazol-6-amine | HCID 81423 | — |
| Reactant | 1-Ethoxyethanol | HCID 10129898 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | 4-Chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile | HCID 11220637 | — |
| Product | HCID 10223129 | HCID 10223129 | 90% |
Reaction Steps
The title compound was prepared by the procedure of Example 166 using 0.311 g of 7-(3-chloro-propoxy)-4-chloro-6-methoxy-quinoline-3-carbonitrile, 0.147 g of 6-aminoimidazole, 0.128 g of pyridine hydrochloride and 12 ml of ethoxyethanol to give 0.367 g (90%) of the desired product. MP 280-285° C. mass spectrum (electrospray m/e): M+H=407.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288082B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-6d5b386feb8745bcbb81926dc7c5af88 |
| Source note | uspto-grants-2001_09 |