Thiophene → HCID 21701047, compound

HRID 1596127Notes

Reaction equation

HRID 1596127 reaction equation
[C:1]([O:6][C:7]([CH3:10])([CH3:9])[CH3:8])(=[O:5])[C:2]([CH3:4])=[CH2:3].[S:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1>O1CCCC1>[CH3:3][C:2]1([C:1]([O:6][C:7]([CH3:10])([CH3:9])[CH3:8])=[O:5])[CH2:4][CH:12]2[S:11][CH:15]1[CH:14]=[CH:13]2

Participants

4

Reactant 2

HCID 8030ThiopheneHCID 11448tert-Butyl methacrylate

Product 1

HCID 21701047HCID 21701047, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
700 °C

Procedure

In tetrahydrofuran solvent (500 g), tert-butyl methacrylate (1.2 mole) of Chemical Formula 3d below and thiophene (1.0 mole) are dissolved, and the solution is introduced into a 2-liter flask. After stirring at 700° C., 10 atm for 24 hours, the solvent and excess amount of tert-butyl methacrylate are removed by using a rotary evaporator. The residue is distilled in vacuo to obtain pure 1,1-dimethylethyl 2-methyl-7-thiabicyclo[2.2.1]hept-5-ene-2-carboxylate of Chemical Formula 125 (yield: 50%).

Workup

  1. additionthe solution is introduced into a 2-liter flask
  2. customthe solvent and excess amount of tert-butyl methacrylate are removed
  3. customa rotary evaporator
  4. distillationThe residue is distilled in vacuo

Sources & evidence

ORD record
ord-2ab38e3cb517419187388e3f5d746dc8
Source dataset
uspto-grants-2001_09
Patent number
US06291131B1

Reaction notes

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