反应详情

温度

700 °C

The compound of Chemical Formula 201, that is 7-thiabicyclo[2.2.1]hept-5ene-2,3-dicarboxylic anhydride (50 g) is well mixed with water (200 ml), and 1 g of hydrochloric acid is added thereto. The resultant mixture is heated under reflux at 700° C. for 20 hours. Upon cooling the mixture to room temperature, crystals are formed. The crystals are dried in vacuo to obtain 7-thiabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid represented by Chemical Formula 167 (yield: 70%).

1. additionis added
2. temperatureUpon cooling the mixture to room temperature
3. customcrystals are formed
4. customThe crystals are dried in vacuo