HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 69843245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonan-9-one | HCID 367172 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 69843245 | HCID 69843245 | — |
Reaction Steps
A solution of 3,7-dibenzyl-3,7-diazabicyclo[3.3.1]nonane-9-one (10.0 g; 29.8 mmol; Bionet), ethylene glycol (20 g) and p-TSA (12.5 g; 65.7 mmol) in toluene (200 mL) was refluxed in a Dean-Stark apparatus for 12 h. NaOH (200 mL, 2M) was added and the organic layer separated, dried and concentrated to give the sub-title compound in a quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06291475B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-882240df5fd64fa98cd1e5fe8b01fd92 |
| Source note | uspto-grants-2001_09 |