Acetic Acid → 8-Methyl-1,1-dioxothiochroman-4-one-7-carboxylic acid

HRID 1596760Notes

Reaction equation

HRID 1596760 reaction equation
[CH3:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][CH:5]=[C:6]2[C:11]=1[S:10][CH2:9][CH2:8][C:7]2=[O:12].OO.[OH2:18].C(O)(=[O:21])C>[O-][W]([O-])(=O)=O.[Na+].[Na+]>[CH3:1][C:2]1[C:3]([C:13]([OH:15])=[O:14])=[CH:4][CH:5]=[C:6]2[C:11]=1[S:10](=[O:21])(=[O:18])[CH2:9][CH2:8][C:7]2=[O:12]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 962WaterHCID 153352288-Methylthiochroman-4-one-7-carboxylic acid

Product 1

HCID 153352298-Methyl-1,1-dioxothiochroman-4-one-7-carboxylic acid

Reagents, catalysts & solvents 1

HCID 26052Sodium tungstateCatalyst

Procedure

20 g (0.09 mol) of 8-methylthiochroman-4-one-7-carboxylic acid are dissolved in 100 ml of acetic acid. One spatula-tip full of sodium tungstate is added. 24.9 g (0.22 mol) of 30% strength hydrogen peroxide solution are then added dropwise at 50° C. Stirring is continued for one hour at RT. The reaction solution is then poured into water, during which process a precipitate is formed, which is filtered off with suction. The product is washed with water and then dried.

Workup

  1. customis formed
  2. filtrationwhich is filtered off with suction
  3. washThe product is washed with water
  4. customdried

Sources & evidence

ORD record
ord-f0e321cbefac4d678f9692038bbf17ed
Source dataset
uspto-grants-2001_09
Patent number
US06291682B1

Reaction notes

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