反应详情

7.0 g (31.5 mmol) of 8-methylthiochroman-4-one-7-carboxylic acid together with one spatula-tip full of sodium tungstate are introduced into 70 ml of acetic acid. 3.6 g (31.5 mmol) of a 30% strength hydrogen peroxide solution are added dropwise at 50° C. Stirring is continued for 3 hours. The reaction solution is then stirred into water. The product is extracted using ethyl acetate. The organic phase is dried and the solvent is removed. The product is purified by chromatography.

1. extractionThe product is extracted
2. customThe organic phase is dried
3. customthe solvent is removed
4. customThe product is purified by chromatography