HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Amino-1-benzyl-4-phenylpiperidine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(1-Benzyl-4-phenylpiperidin-4-YL)acetamide | HCID 18964199 | — |
| Product | 4-Amino-1-benzyl-4-phenylpiperidine dihydrochloride | HCID 22741800 | — |
Reaction Steps
The compound prepared in stage B is hydrolyzed by refluxing for 3 hours in 6N HCl. After evaporation to dryness, the residue is dissolved in methanol, crystallized by addition of acetone, filtered and dried to give the expected compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294537B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-4fc259e5c81e47e6b2e634d060d6d6e0 |
| Source note | uspto-grants-2001_09 |