Hydrochloric Acid → HCID 178439630, compound

HRID 1597369Notes

Reaction equation

HRID 1597369 reaction equation
[NH:1]1[CH:5]=[C:4]([CH:6]([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[N:12]=[CH:11][CH:10]=2)[CH2:7][CH3:8])[N:3]=[CH:2]1.[ClH:19]>CO.O1CCOCC1>[ClH:19].[ClH:19].[NH:1]1[CH:5]=[C:4]([CH:6]([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[N:12]=[CH:11][CH:10]=2)[CH2:7][CH3:8])[N:3]=[CH:2]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 178439629HCID 178439629, compound

Product 1

HCID 178439630HCID 178439630, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 312751,4-DioxaneSolvent

Procedure

To 4-[1-(1H-Imidazol-4-yl)-propyl]-quinoline (0.185, 0.779 mmol) in 5 ml methanol, 3 ml of HCl in dioxane was added and the reaction mixture was concentrated under reduced pressure to give 0.240 g, (100%) of the product as a foam.

Workup

  1. concentrationthe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-cb564ccd3c8c45149260f0193102cd47
Source dataset
uspto-grants-2001_09
Patent number
US06294566B1

Reaction notes

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