Methanol → 1-[3-(5-Chloro-thiophen-2-yl)-4-(tetrahydro-pyran-4-yloxy)-phenyl]-ethylamine
Reaction equation
[C:25](#[N:26])[BH3-:27].[CH3:23][OH:24].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:7]2[cH:8][c:9]([C:20]([CH3:21])=[O:22])[cH:10][cH:11][c:12]2[O:13][CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[s:6]1.[Na+:28].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:7]2[cH:8][c:9]([CH:20]([CH3:21])[NH2:26])[cH:10][cH:11][c:12]2[O:13][CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[s:6]1Participants
6
Sources & evidence
- ORD record
- ord-eb4c3697cf324371923e28dc4e9a3a8c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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