196809-80-0 → HCID 54388575, compound

HRID 1597449Notes

Reaction equation

HRID 1597449 reaction equation
[CH3:1][N:2]([CH3:10])[CH2:3][CH2:4][CH2:5][NH:6][C:7]([NH2:9])=[S:8].Br[CH:12]([CH3:20])[C:13](=O)[CH2:14][C:15]([O:17][CH3:18])=[O:16]>>[CH3:18][O:17][C:15](=[O:16])[CH2:14][C:13]1[N:9]=[C:7]([NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:10])[CH3:1])[S:8][C:12]=1[CH3:20]

Participants

3

Reactant 2

HCID 1810294196809-80-0HCID 9815681Methyl 4-bromo-3-oxopentanoate

Product 1

HCID 54388575HCID 54388575, compoundYield 50.8%

Procedure

The title compound (854 mg) was prepared from 1.0 g (6.20 mmol) of 3-dimethylaminopropyl thiourea and 1.30 g (6.20 mmol) of methyl 4-bromo-3-oxo-pentanoate according to the method of Intermediate 45: low resolution MS (FAB)m/e 272 (M+).

Sources & evidence

ORD record
ord-3a08ee800cde48339ceb25e9fc99ad74
Source dataset
uspto-grants-2001_09
Patent number
US06294580B1

Reaction notes

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