反应详情

Ester 6-1 (324 mg, 1.22 mmol) was dissolved in 6 mL EtOH, then 1 N NaOH (2.4 mL, 2.4 mmol) was added. After stirring overnight the mixture was concentrated, rediluted with EtOAc, extracted into 10% KHSO4, then concentrated, providing acid 6-2, along with inorganic salts.

1. concentrationwas concentrated
2. additionrediluted with EtOAc
3. extractionextracted into 10% KHSO4
4. concentrationconcentrated