HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-(Pyridin-4-yl)butanoyl-sarcosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(Pyridin-4-yl)butanoyl-sarcosine ethyl ester | HCID 21699762 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(Pyridin-4-yl)butanoyl-sarcosine | HCID 20689265 | — |
Reaction Steps
Ester 6-1 (324 mg, 1.22 mmol) was dissolved in 6 mL EtOH, then 1 N NaOH (2.4 mL, 2.4 mmol) was added. After stirring overnight the mixture was concentrated, rediluted with EtOAc, extracted into 10% KHSO4, then concentrated, providing acid 6-2, along with inorganic salts.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06294549B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-a5515b61493b4f96bc3379e8cfaad037 |
| Source note | uspto-grants-2001_09 |