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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597925Generated: October 31, 2026

1,2,3,4-Tetrahydroquinoline → HCID 18770805, compound

https://huagongshe.com/reaction/1597925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-TetrahydroquinolineHCID 69460—
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
SolventIsopropanolHCID 3776—
ProductHCID 18770805HCID 1877080591%

Reaction Steps

Utilizing a procedure analogous to that described in Example 2, this product was prepared in 91% yield from 1,2,3,4-tetrahydroquinoline (2 eq.) and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 130°-131° C.; LC-MS: 322 (MH+); anal. RP18-HPLC RT: 4.08 min.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736534
Source datasetuspto-grants-1998_04
ORD IDord-2fcc71a4386d49da92fdc0362d2b733d
Source noteuspto-grants-1998_04