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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597926Generated: November 4, 2026

6-Methyl-1,2,3,4-tetrahydroquinoline → HCID 18932846, compound

https://huagongshe.com/reaction/1597926

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methyl-1,2,3,4-tetrahydroquinolineHCID 66678—
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
SolventIsopropanolHCID 3776—
ProductHCID 18932846HCID 1893284694%

Reaction Steps

Utilizing a procedure analogous to that described in Example 2, this product was prepared in 94% yield from 6-methyl-1,2,3,4-tetrahydroquinoline (2 eq.) and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 147°-148° C.; LC-MS: 336 (MH+); anal. RP18-HPLC RT: 4.51 min.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736534
Source datasetuspto-grants-1998_04
ORD IDord-97dff889a47f4932980fa92dba59c955
Source noteuspto-grants-1998_04