HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6,7-dimethoxyquinazoline → HCID 18932793, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinazoline | HCID 2769364 | — |
| Reactant | 2,3-dihydro-1H-indol-2-ylmethanol | HCID 2794664 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 18932793 | HCID 18932793 | 57% |
Reaction Steps
Utilizing a procedure analogous to that described in Example 1, this product was prepared in 57% yield from 2-hydroxymethyl-indoline (1 eq.) and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 145.5°-147° C.; LC-MS: 338 (MH+); anal. RP18-HPLC RT: 4.03 min.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736534 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-02b274695d154e58830826f0869097ec |
| Source note | uspto-grants-1998_04 |