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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1597947Generated: October 30, 2026

4-Chloro-6,7-dimethoxyquinazoline → HCID 18932858, compound

https://huagongshe.com/reaction/1597947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
ReactantHCID 14344794HCID 14344794—
SolventIsopropanolHCID 3776—
ProductHCID 18932858HCID 1893285843%

Reaction Steps

Utilizing a procedure analogous to that described in Example 1, this product was prepared in 43% yield from 6-isopropyl-indoline (1.1 eq.), and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in i-PrOH. (M.P. 128°-129° C.; LC-MS: 350 (MH+); anal. RP18-HPLC RT: 5.51 min.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05736534
Source datasetuspto-grants-1998_04
ORD IDord-f92ec11c9ab6468192bda3085fb526d2
Source noteuspto-grants-1998_04