HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 18932865, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 6-Chloro-2,3-dihydro-1h-indole | HCID 258567 | — |
| Reactant | HCID 18932829 | HCID 18932829 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 18932865 | HCID 18932865 | — |
Reaction Steps
4-Chloro-6-(4-methylpiperazin-1-yl)-quinazoline hydrochloride (537 mg, 1.80 mmol) and 6-chloroindoline (169 mg, 1.10 mmol) were refluxed in 10 mL of 1,2-dichloroethane and pyridine (350 mg, 4.40 mmol) for 48 hours. The product was isolated as the (58%); using the analogous method of Example 120; 267 mg (58%); M.P. 289°-290° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736534 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-c12375d8737a4a35ac2068a81083ae6a |
| Source note | uspto-grants-1998_04 |