HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6,7-dimethoxyquinazoline → HCID 18932772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinazoline | HCID 2769364 | — |
| Reactant | HCID 18932749 | HCID 18932749 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 18932772 | HCID 18932772 | 93% |
Reaction Steps
Utilizing a procedure analogous to that described in Example 47, this product was prepared in 93% yield from 6-trimethylsilanylethynyl-indoline (1.1 eq.), and 4-chloro-6,7-dimethoxy-quinazoline (1.0 eq) in N-methyl-pyrrolidinone. (LC-MS: 404 (MH+); anal. RP18-HPLC RT: 6.49 min.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736534 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-06ccb60163434e1b8aa3eceb4d4874a4 |
| Source note | uspto-grants-1998_04 |