HRID1598446

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@@H]1Cc1ccccc1

HCID22884141

1,1-Dimethylethyl (2S)-2,4-bis(phenylmethyl)-1-piperazinecarboxylate

C23H30N2O2

PRODUCTS

产物

反应SMILES：CC(C)(C)OC(=O)N1CCNC[C@@H]1Cc1ccccc1

HCID17750441

tert-Butyl (2S)-2-benzylpiperazine-1-carboxylate

C16H24N2O2

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Example 2, Step C, except using 1-tert-butoxycarbonyl-2(S),4-dibenzylpiperazine (4.78 g, 11.3 mmol) and 10% palladium on carbon (1.04 g). The title compound was obtained as an oil. NMR (300 MHz, CD3OD) δ 7.25 (5H, m), 4.35 (1H, m), 4.00 (1H, d, J=12 Hz), 2.7-3.3 (7H, m), 1.25 (9H, s).

WORKUP

后处理

customThe title compound was prepared