HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl 4-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate → 1-tert-Butyl 3-methyl piperazine-1,3-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl 4-tert-butyl 2-methyl piperazine-1,2,4-tricarboxylate | HCID 4451965 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-tert-Butyl 3-methyl piperazine-1,3-dicarboxylate | HCID 2756819 | — |
Reaction Steps
A solution of the product from step A in methanol was hydrogenated at 60 psi in the presence of 10% Pd/C (0.250 g) for 24h. The catalyst was filtered and the methanol evaporated to yield the title compound as an oil (0.91 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05736539 |
| Source dataset | uspto-grants-1998_04 |
| ORD ID | ord-c1c799a041a9478e925a1801265ae039 |
| Source note | uspto-grants-1998_04 |