反应详情

In 100 ml of tetrahydrofuran was suspended 5.7 g of lithium aluminum hydride, and to the suspension was added dropwise 18.9 g of 2-propionyl aminoindane dissolved in 150 ml of tetrahydrofuran. The mixture was refluxed under heating for 2 hours. After cooling, excessive lithium aluminum hydride was treated with a saturated ammonium chloride aqueous solution, and insolubles were removed by filtration. The filtrate was condensed, and chloroform was added to the residue. After the mixture was washed with 10 water and dried, the solvent was removed to obtain 17.5 g of 2-propylaminoindane.

1. temperatureThe mixture was refluxed
2. temperatureunder heating for 2 hours
3. temperatureAfter cooling
4. customwere removed by filtration
5. customcondensed, and chloroform
6. additionwas added to the residue
7. washAfter the mixture was washed with 10 water
8. customdried
9. customthe solvent was removed