Triethylamine → HCID 86752387, compound

HRID 1598565Notes

Reaction equation

HRID 1598565 reaction equation
N[CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:8]=2)[CH2:3]1.ClCC[S:21](Cl)(=[O:23])=[O:22].C([N:27]([CH2:30][CH3:31])CC)C>>[CH:2]([CH:3]1[CH2:4][C:5]2[C:31](=[CH:9][CH:8]=[C:7]([C:11]3[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:6]=2)[CH:30]1[N:27]=[S:21](=[O:22])=[O:23])=[CH2:10]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 15385Ethanesulfonylchloride, 2-chloro-HCID 140714996-(2-amino-indan-5-yl)-4,5-dihydropyridazin-3(2H)-one

Product 1

HCID 86752387HCID 86752387, compound

Procedure

2-Amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane was treated with chloroethanesulfonyl chloride in the presence of two equivalent amounts of triethylamine in the same manner as in Example 2 to obtain 2-vinyl sulfonylamino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane.

Sources & evidence

ORD record
ord-22f35dbc241f40118575c71ca10b54ab
Source dataset
uspto-grants-1998_04
Patent number
US05739132

Reaction notes

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