Hydrochloric Acid → 4-(3-Chloro-4-fluorophenyl)-6-methyl-N-(1-(6-methylpyrimidin-4-yl)piperidin-4-yl)benzo[d]thiazol-2-amine

HRID 159857Notes

Reaction equation

HRID 159857 reaction equation
[Br:1][c:2]1[s:3][c:4]2[c:5]([n:6]1)[c:7](-[c:12]1[cH:13][c:14]([Cl:19])[c:15]([F:18])[cH:16][cH:17]1)[cH:8][c:9]([CH3:11])[cH:10]2.[CH3:22][c:23]1[cH:24][c:25]([N:29]2[CH2:30][CH2:31][CH:32]([NH2:35])[CH2:33][CH2:34]2)[n:26][cH:27][n:28]1.[ClH:20].[ClH:21]>>[c:2]1([NH:35][CH:32]2[CH2:31][CH2:30][N:29]([c:25]3[cH:24][c:23]([CH3:22])[n:28][cH:27][n:26]3)[CH2:34][CH2:33]2)[s:3][c:4]2[c:5]([n:6]1)[c:7](-[c:12]1[cH:13][c:14]([Cl:19])[c:15]([F:18])[cH:16][cH:17]1)[cH:8][c:9]([CH3:11])[cH:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 166433141-(6-Methylpyrimidin-4-yl)piperidin-4-amineHCID 673424052-Bromo-4-(3-chloro-4-fluorophenyl)-6-methylbenzo[d]thiazole

Product 1

HCID 866567144-(3-Chloro-4-fluorophenyl)-6-methyl-N-(1-(6-methylpyrimidin-4-yl)piperidin-4-yl)benzo[d]thiazol-2-amine

Sources & evidence

ORD record
ord-bc36a2bc074049cab2b5a76f64297d19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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