Diisopropyl Ether → HCID 18929757, compound

Participants

Reaction Steps

In 8 ml of a 25% hydrogen bromide-acetic acid solution was suspended 1.41 g of 2-[4,5-dihydropyridazin-3(2H)-on-6-yl]-5-[(2-methylphenyl)sulfonylamino]-4,5,6,7-tetrahydrobenzo-[b]thiophene, and 0.25 ml of dimethylsulfoxide was added thereto. The mixture was stirred at room temperature for 2 hours. Then, diisopropyl ether was added to the reaction mixture, and crystals precipitated were collected by filtration to obtain 1.00 g of 2-[pyridazin-3(2H)-on-6-yl]-5-[(2-methylphenyl)sulfonylamino]-4,5,6,7-tetrahydrobenzo[b]thiophene.

Provenance & Evidence