反应详情

To a suspension of 7-bromo-2,3-dihydro-10-hydroxypyridazino-[4,5-b]quinoline-1,4-dione (0.600 g, 1.95 mM) in methanol (20 mL) was added choline hydroxide (0.24 g, 1.98 mM, 45% solution in methanol). The resulting solution was concentrated and the solid yellow residue was recrystallized from ethanol to provide (0.62 g, 78%) the title compound as yellow crystals, mp 227.5°-228.5° C.

1. concentrationThe resulting solution was concentrated
2. customthe solid yellow residue was recrystallized from ethanol