Trifluoroacetic acid → HCID 15345708, compound

HRID 1598819Notes

Reaction equation

CO[C:3]1[CH:13]=[C:12]([C@@H:14]2[CH2:16][C@H:15]2[C:17](=[O:28])[C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH2:25][CH2:26][NH2:27])[CH:19]=2)[CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([OH:9])=[O:8].F[C:30](F)(F)C(O)=O>>[NH2:27][CH2:26][CH2:25][O:24][C:20]1[CH:19]=[C:18]([CH:23]=[CH:22][CH:21]=1)[C:17]([C:15]1[CH:14]=[C:12]2[C:13](=[CH:30][CH:16]=1)[CH:3]=[C:4]([O:5][CH2:6][C:7]([OH:9])=[O:8])[CH:10]=[CH:11]2)=[O:28]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 131719426HCID 131719426, compound

Product 1

HCID 15345708HCID 15345708, compound

Procedure

Ex. 315. (+/-)-trans-[[2-methoxy-4-[2-((3-(2-aminoethoxy)benzoyl))cyclopropyl]phenoxy]]acetic acid.trifluoroacetic acid. MS(NH3): 404 (5%, M+NH4), 386 (base, M+H).

Sources & evidence

ORD record: ord-6c311e1cf9914e538b2b6423b6475bc0
Source dataset: uspto-grants-1998_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05739163

Reaction notes

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