1-Adamantanecarbonyl chloride → HCID 18930566, compound

HRID 1598911Notes

Reaction equation

HRID 1598911 reaction equation
F[C:2]1[CH:30]=[CH:29][CH:28]=[CH:27][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][C:13](=[O:26])[CH2:14][NH:15][C:16]([O:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:17])=[O:5].[C:31]12(C(Cl)=O)[CH2:40]C3CC(CC(C3)[CH2:32]1)[CH2:38]2>>[C:3]12([C:4]([C:6]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[NH:12][C:13](=[O:26])[CH2:14][NH:15][C:16]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:17])=[O:5])[CH2:40][CH:31]3[CH2:38][CH:28]([CH2:29][CH:30]([CH2:32]3)[CH2:2]1)[CH2:27]2

Participants

3

Reactant 2

HCID 989151-Adamantanecarbonyl chlorideHCID 18930608HCID 18930608, compound

Product 1

HCID 18930566HCID 18930566, compoundYield 6%

Procedure

According to the method used for the synthesis of the compound 28a, the titled compound (110 mg) is synthesized by using tert-butyl((2-trimethylstannylphenyl)-(2-(3-motolylureido)acethyl)amino)acetate (2.5 g) and adamantane-1-carbonylchloride (866 mg). Yield 6%.

Sources & evidence

ORD record
ord-c1bed4338b35422688aeda4fb9a60c3f
Source dataset
uspto-grants-1998_04
Patent number
US05739162

Reaction notes

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