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HRID1599152

反应详情

EQUATION

反应方程式

HRID 1599152 的结构方程式

REACTANTS

反应物

2
结构：[C-]#N.[K+]
HCID9032

Potassium cyanide

CKN

结构：Cc1ccc(S(=O)(=O)OCC2CC3CN(C(=O)Cc4ccccc4N4CCCC4)CC3C(O)(c3ccccc3F)C2)cc1
HCID86752419

未命名化合物

PRODUCTS

生成物

1
结构：N#CCC1CC2CN(C(=O)Cc3ccccc3N3CCCC3)CC2C(O)(c2ccccc2F)C1
HCID86752418

未命名化合物

收率 45.1%

PROCEDURE

实验过程

The procedure is as described for Example 13, starting from 0.07 g of (3aRS,4RS,6SR,7aSR)-6-p-toluenesulphonyloxymethyl-4-(2-fluorophenyl)-2-[2-(1-pyrrolidinyl)phenylacetyl]perhydroisoindol-4-ol and 0.015 g of potassium cyanide, and gives 0.024 g of (3aRS,4RS,6SR,7aSR)-6-cyanomethyl-4-(2-fluorophenyl)-2-[2-(1-pyrrolidinyl)phenylacetyl]perhydroisoindol-4-ol in the form of a thick white foam.