反应详情

温度

70 °C

2--Chloro-5-nitro benzene sulphonylchloride (40 parts) was stirred in p-dioxane (48 parts) at room temperature. Potassium fluoride (10 parts) dissolved in water (35 parts) was added, and the mixture heated to 70° C. Stirred at 70° C. for 4 hours then cooled to room temperature and poured onto ice/water. Allowed to stand for 2 days then filtered off the precipitate and dried in air to yield the product 2-chloro-5-nitro benzene sulphonylfluoride (36 parts).

1. additionwas added
2. temperaturethen cooled to room temperature
3. additionpoured onto ice/water
4. waitAllowed to stand for 2 days
5. filtrationthen filtered off the precipitate
6. customdried in air