反应详情

The 2-chloro-5-nitro benzene sulphonylfluoride (2.4 parts) was stirred. in glacial acetic acid (25 parts) with iron powder (2 parts). Heated to reflux and stirred at reflux for 2.5 hours, then cooled to room temperature, poured onto ice/water and allowed to stand at room temperature overnight. The resultant precipitate was filtered off and dried in air to yield the product 2-chloro-5-amino benzene sulphonylfluoride (0.8 parts).

1. temperatureHeated
2. temperatureto reflux
3. temperatureat reflux for 2.5 hours
4. additionpoured onto ice/water
5. filtrationThe resultant precipitate was filtered off
6. customdried in air