HCID 18928135, compound → HCID 18928117, compound

Participants

Reaction Steps

2-Ethoxycarbonyl-1-phosphonomethyl-7-trifluoromethylimidazo[1,2-a]quinoxalin-4(5H)-one (example 30) (210 mg, 0.5 mmol) in hydrobromic acid (48% in water) (20 ml) was stirred at 80° C. for 16 h. The mixture was concentrated in vacuo and the residue stirred with ether. The product, which was isolated by filtration was washed with cold water to afford 190 mg (97%) of the title compound. M.p. >250° C.

Provenance & Evidence