Hydrochloric Acid → Phenyl octanoate

HRID 1599522Notes

Reaction equation

HRID 1599522 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:8](O)(=[O:16])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].S(=O)=O.Cl>S(Cl)(Cl)=O>[C:8]([O:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:16])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 379Octanoic AcidHCID 996PhenolHCID 1119Sulfur Dioxide

Product 1

HCID 229895Phenyl octanoate

Reagents, catalysts & solvents 1

HCID 24386Thionyl ChlorideSolvent

Procedure

The ester was prepared by slowly adding thionyl chloride (10 ml) to a mixture of pure phenol (6.5 g) and octanoic acid (10 g). The reaction mixture was warmed to drive off the sulfur dioxide and hydrogen chloride gases. The crude mixture was distilled at 95°-100° C./5 mmHg.

Workup

  1. temperatureThe reaction mixture was warmed
  2. distillationThe crude mixture was distilled at 95°-100° C./5 mmHg

Sources & evidence

ORD record
ord-2c67f39815a040c1b539b782c2b2c497
Source dataset
uspto-grants-1998_04
Patent number
US05741821

Reaction notes

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