4-Chlorobenzaldehyde → HCID 67680621, compound

HRID 1599790Notes

Reaction equation

HRID 1599790 reaction equation
[CH2:1]1[C:3]2([CH2:7][CH2:6][CH2:5][C:4]2=[O:8])[CH2:2]1.[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=O)=[CH:12][CH:11]=1>[OH-].[Na+]>[Cl:9][C:10]1[CH:17]=[CH:16][C:13]([CH:14]=[C:5]2[CH2:6][CH2:7][C:3]3([CH2:2][CH2:1]3)[C:4]2=[O:8])=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 77264-ChlorobenzaldehydeHCID 258618Spiro[2.4]heptan-4-one

Product 1

HCID 67680621HCID 67680621, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

It is known that spiro-[2.4]-heptan-4-one can be reacted with 4-chlorobenzaldehyde in methanolic sodium hydoxide solution to give 5-(4-chlorobenzylidene)spiro[2.4]-heptan-4-one (see DE-A 43 20 498, Example 1). A disadvantage is the extremely long reaction time required, of 50 hours.

Sources & evidence

ORD record
ord-378930c038c743f0aaafc14bf50af133
Source dataset
uspto-grants-1998_04
Patent number
US05741937

Reaction notes

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