Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | HCID 69944581 | HCID 69944581 | — |
| Product | HCID 15908416 | HCID 15908416 | 61% |
Reaction Steps
A suspension of 0.50 g of 5-chloro-6-chloro-methyluracil and 0.22 g of methyl isothiocyanate in N,N-dimethylformamide (3 ml) was heated at 70° C. for 4 hours under stirring. Water (50 ml) was added to the reaction mixture. A crystallized matter was collected by filtration and then washed with water and methanol, whereby 435 mg of the title compound were obtained (yield: 61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05744475 |
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| Source dataset | uspto-grants-1998_04 |
|---|
| ORD ID | ord-b426eab68d5746e299e5f2f1ac2935a2 |
|---|
| Source note | uspto-grants-1998_04 |
|---|
