Isobutyryl chloride → HCID 19365545, compound

HRID 1600063Notes

Reaction equation

[C:1]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[S:32][C:16]3[N:17]([CH2:23][C:24]4[C:29]([F:30])=[CH:28][CH:27]=[CH:26][C:25]=4[F:31])[CH:18]=[C:19]([OH:22])[C:20](=[O:21])[C:15]=3[C:14]=2[CH2:33][N:34]([CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)[CH3:35])=[CH:9][CH:8]=1)(=[O:5])[CH:2]([CH3:4])[CH3:3].[C:43]([Cl:48])(=[O:47])[CH:44]([CH3:46])[CH3:45]>>[ClH:48].[C:1]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([C:13]2[S:32][C:16]3[N:17]([CH2:23][C:24]4[C:25]([F:31])=[CH:26][CH:27]=[CH:28][C:29]=4[F:30])[CH:18]=[C:19]([O:22][C:43](=[O:47])[CH:44]([CH3:46])[CH3:45])[C:20](=[O:21])[C:15]=3[C:14]=2[CH2:33][N:34]([CH2:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)[CH3:35])=[CH:11][CH:12]=1)(=[O:5])[CH:2]([CH3:4])[CH3:3]

Participants

Reactant 2

HCID 62325Isobutyryl chloride

HCID 19365563HCID 19365563, compound

Product 1

HCID 19365545HCID 19365545, compound

Procedure

The compound obtained in Example 9 was subjected to a similar procedure as in Example 10, using isobutyryl chloride instead of isopropyl chloride, and the titled compound was obtained.

Sources & evidence

ORD record: ord-9bdee73746e845749a0e2c453a2ce142
Source dataset: uspto-grants-1998_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05744479

Reaction notes

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