HRID1600107

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID516892

Sodium Bicarbonate

CHNaO3

结构：CC(=O)N(CC1CC(SC2=C(C(=O)OCc3ccc([N+](=O)[O-])cc3)N3C(=O)C(C(C)O)C3C2C)CO1)OCc1ccccc1

HCID131719844

未命名化合物

PRODUCTS

生成物

结构：CC(=O)N(CC1CC(SC2=C(C(=O)[O-])N3C(=O)C(C(C)O)C3C2C)CO1)OCc1ccccc1.[Na+]

HCID131719843

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

The title compound is prepared by the procedure of Example 18 using 0.272 gof product from Example 74, 0.0402 g of sodium bicarbonate, 2 ml of water, 11.3 ml of dioxane, and 0.110 g of 10% palladium/carbon to give 0.059 g ofthe desired product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8b9c87c8ac994b7a90592e76a2810130
来源数据集: uspto-grants-1998_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05744465
来源说明: uspto-grants-1998_04

反应 SMILES

[N+](C1C=CC(C[O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:40])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][N:28]([C:37](=[O:39])[CH3:38])[O:29][CH2:30][C:31]4[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=4)[O:24][CH2:23]2)[CH:17]([CH:41]([OH:43])[CH3:42])[C:16]3=[O:44])=[O:13])=CC=1)([O-])=O.C(=O)(O)[O-].[Na+:49].O>[Pd].O1CCOCC1>[Na+:49].[C:37]([N:28]([CH2:27][CH:25]1[O:24][CH2:23][CH:22]([S:21][C:20]2[CH:19]([CH3:40])[CH:18]3[N:15]([C:16](=[O:44])[CH:17]3[CH:41]([OH:43])[CH3:42])[C:14]=2[C:12]([O-:13])=[O:11])[CH2:26]1)[O:29][CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)(=[O:39])[CH3:38]