Acetonitrile → HCID 22869819, compound

HRID 1600117Notes

Reaction equation

HRID 1600117 reaction equation
[N:1]([CH2:4][C@@H:5]1[O:10][CH2:9][C@@H:7](O)[CH2:6]1)=[N+:2]=[N-:3].C([O-])(=[S:13])C.[K+].C(#N)C>C(OCC)(=O)C.CCCCCC>[N:1]([CH2:4][C@@H:5]1[O:10][CH2:9][C@H:7]([SH:13])[CH2:6]1)=[N+:2]=[N-:3]

Participants

5

Reactant 3

HCID 6342AcetonitrileHCID 23670855Potassium ethanethioateHCID 131720629HCID 131720629, compound

Product 1

HCID 22869819HCID 22869819, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound is prepared by the procedure of Example 111 using 2.22 gof product from Example 116, 1.01 g of potassium thioacetate and 25 ml of acetonitrile to give 0.90 g of the desired product after chromatography (silica gel: 30% ethyl acetate/hexane). IR(neat): 2100 and 1692 cm-1.

Sources & evidence

ORD record
ord-0aacd31026024d6f814d2fdd24fdfb06
Source dataset
uspto-grants-1998_04
Patent number
US05744465

Reaction notes

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