Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,6-Lutidine | HCID 7937 | — |
| Reactant | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Reactant | 1,4-Dioxa-8lambda4-thiaspiro(4.5)decan-8-one | HCID 13273782 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18923997 | HCID 18923997 | — |
Reaction Steps
A mixture of 0.88 g of product from Example 393, 5.0 ml of acetic anhydrideand 2.0 ml of lutidine is heated at 110°-115° C. for 2.5 hours, followed by increasing the temperature to 150° C. and then heated for 3 hours. The reaction mixture is diluted with ethyl acetate, washed 2 X with 1N hydrochloric acid, water, saturated sodium chloride, dried and concentrated in vacuo. The residue is dissolved in methylene chloride, filtered through a pad of hydrous magnesium silicate and reconcentrated in vacuo to give 0.569 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05744465 |
|---|
| Source dataset | uspto-grants-1998_04 |
|---|
| ORD ID | ord-af2eb8983c2b4a768ca8a7a1a5f60dc1 |
|---|
| Source note | uspto-grants-1998_04 |
|---|
