Hydrochloric Acid → HCID 131721429, compound

HRID 1600526Notes

Reaction equation

HRID 1600526 reaction equation
[ClH:1].C(OC([NH:9][C@H:10]([C:18]([O:20][CH2:21][CH2:22][SiH3:23])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O)(C)(C)C>O1CCOCC1>[ClH:1].[SiH3:23][CH2:22][CH2:21][O:20][C:18](=[O:19])[C@H:10]([CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[NH2:9]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 131721430HCID 131721430, compound

Product 1

HCID 131721429HCID 131721429, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

30 mL of a 4.0 M solution of HCl in dioxane was added to the Boc-PheOSET from the previous step. The mixture was stirred for 90 minutes. The solvents were evaporated, giving a waxy solid, phenylalanine silylethyl ester hydrochloride (HCl.PheOSET).

Workup

  1. customThe solvents were evaporated

Sources & evidence

ORD record
ord-e985649372374b1486d27c3c9d579bb2
Source dataset
uspto-grants-1999_11
Patent number
US05976858

Reaction notes

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