Glycine → L-Isoleucine

HRID 1600579Notes

Reaction equation

HRID 1600579 reaction equation
[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=CC=CC=1.N[C@H:14](C(O)=O)C(C)C.N[C@H](C(O)=O)CC(C)C.N[C@H](C(O)=O)CC1C2C(=CC=CC=2)NC=1.N[C@H](C(O)=O)CCSC.NCC(O)=O.N[C@H](C(O)=O)CS.N[C@H](C(O)=O)CC1C=CC(O)=CC=1.N[C@H](C(O)=O)[C@@H](C)O.N[C@H](C(O)=O)CCC(=O)O.N[C@H](C(O)=O)CC(=O)N.N[C@H](C(O)=O)CCC(=O)N.N[C@H](C(O)=O)CC(=O)O.N[C@H](C(O)=O)CCCCN.N[C@H](C(O)=O)CCCNC(=N)N>>[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[C@H:3]([CH2:4][CH3:9])[CH3:14]

Participants

16

Reactant 15

HCID 750GlycineHCID 5862L-(+)-CysteineHCID 5960L-Aspartic AcidHCID 5961L-GlutamineHCID 5962L-LysineHCID 6057L-TyrosineHCID 6106L-LeucineHCID 6137L-MethionineHCID 6140L-PhenylalanineHCID 6267(-)-AsparagineHCID 6287L-ValineHCID 6288L-ThreonineHCID 6305L-TryptophanHCID 33032L-Glutamic AcidHCID 178418600HCID 178418600, compound

Product 1

HCID 6306L-Isoleucine

Procedure

Phe 0.61; Val 0.54; Leu 0.53; Trp 0.37; Met 0.26 Ala 0.25; Gly 0.16; Cys 0.04; Tyr 0.02; Pro -0.07; Thr -0.18; Ser -0.26; His -0.40; Glu -0.62; Asn -0.64; Gln -0.69; Asp -0.72; Lys -1.10; Arg -1.76.

Sources & evidence

ORD record
ord-2ef6a998a9654d068a189fb4a09f07bd
Source dataset
uspto-grants-1999_11
Patent number
US05977070

Reaction notes

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