Hydrogen Bromide → HCID 54472994, compound

HRID 1600586Notes

Reaction equation

[CH3:1][NH:2][C:3]1[S:4][CH:5]=[C:6]([C:8]2[C@:9]3([CH2:26][CH2:25][C@H:24]4[C@@H:14]([CH2:15][CH:16]=[C:17]5[C@:22]4([CH3:23])[CH2:21][CH2:20][C@H:19]([OH:27])[CH2:18]5)[C@@H:11]3[CH2:12][CH:13]=2)[CH3:10])[N:7]=1.Br>>[CH3:1][NH:2][C:3]1[S:4][CH:5]=[C:6]([C:8]2[C@:9]3([CH2:26][CH2:25][C@H:24]4[C@@H:14]([CH2:15][CH:16]=[C:17]5[C@:22]4([CH3:23])[CH2:21][CH2:20][C:19](=[O:27])[CH2:18]5)[C@@H:11]3[CH2:12][CH:13]=2)[CH3:10])[N:7]=1

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 22878212HCID 22878212, compound

Product 1

HCID 54472994HCID 54472994, compound

Procedure

In an analogous manner to example 2 the title compound is prepared from (3β)-17-[2-(methylamino)-4-thiazolyl]-androsta-5,16-dien-3-ol.HBr prepared in example 3.

Sources & evidence

ORD record: ord-00e6992e483c4cfd9b91ce7e937ff861
Source dataset: uspto-grants-1999_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05977094

Reaction notes

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