HRID1600692

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7503

Benzyl chloride

C7H7Cl

HCID11266913

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

C15H18N2O3

PRODUCTS

生成物

结构：CCOC(=O)c1cc2cc(N3CCN(Cc4ccccc4)CC3)ccc2o1

HCID23508728

Ethyl 5-[4-(phenylmethyl)-1-piperazinyl]-2-benzofurancarboxylate

C22H24N2O3

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

A solution of 1 g of ethyl 5-(1-piperazinyl)-benzofuran-2-carboxylate in 50 ml of dichloromethane is treated with 1 g of benzyl chloride and stirred for 2 hours. After customary working up, ethyl 5-(4-benzyl-1-piperazinyl)benzofuran-2-carboxylate, m.p. 219-222°, is obtained.