HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (+/-)-1-(3'-Chlorobiphenyl-4-yloxy)-4-(3-pyridyl)-2-butanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(3-Chlorophenyl)phenol | HCID 14468005 | — |
| Reactant | HCID 22465338 | HCID 22465338 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (+/-)-1-(3'-Chlorobiphenyl-4-yloxy)-4-(3-pyridyl)-2-butanol | HCID 21830621 | — |
Reaction Steps
Prepared according to the method described in Example 24b) from (±)-α-(chloromethyl)-3-pyridinepropanol (1.0 g), 3'-chlorobiphenyl-4-ol (1.4 g), ethanol (30 ml) and aqueous sodium hydroxide (1.5 M, 5 ml) to give the title compound after purification as a white solid (0.34 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977105 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-5cd02a25f8794cbb8ea7f57fab454624 |
| Source note | uspto-grants-1999_11 |