反应详情

Solid 3'-carboxybiphenyl-4-ol (1.5 g) was suspended in methanol (10 ml) and concentrated sulfuric acid (1 ml). The mixture was heated at reflux for 16 hours. After cooling, the mixture was basified by the addition of solid sodium hydrogen carbonate. The white solid which formed was filtered and washed with copious amounts of water to give the sub-title compound as a white solid (1.5 g).

1. temperatureThe mixture was heated
2. temperatureat reflux for 16 hours
3. temperatureAfter cooling
4. customThe white solid which formed
5. filtrationwas filtered
6. washwashed with copious amounts of water