HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (+/-)-4-(3-Pyridyl)-1-(4-(thiazol-2-yl)phenoxy)-2-butanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(1,3-Thiazol-2-yl)phenol | HCID 223840 | — |
| Reactant | HCID 22465338 | HCID 22465338 | — |
| Solvent | Water | HCID 962 | — |
| Product | (+/-)-4-(3-Pyridyl)-1-(4-(thiazol-2-yl)phenoxy)-2-butanol | HCID 21830668 | — |
Reaction Steps
Prepared according to the method as described in Example 24b) from 2-(4-hydroxyphenyl)thiazole (1 g), ethanol (20 ml), sodium hydroxide (0.255 g), water (5 ml) and (±)-α-(chloromethyl)-3-pyridinepropanol (1 g, from Example 24a)) to give the title compound after purification as a white solid (0.42 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05977105 |
| Source dataset | uspto-grants-1999_11 |
| ORD ID | ord-c5d261493cdc4369a10e098ff8a4abb3 |
| Source note | uspto-grants-1999_11 |